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Original Summaries of Selected CANCERLIT Abstracts.
Breast Cancer and NSAIDS
Last modified on:
Tuesday, April 20, 1999 10:52:30
Copyright © 1994-2008, Information Ventures, Inc.
An aspirin a day keeps the surgeon away? A study (ICDB/95613231) suggests there is a grain of truth to this. The 5-year history of ingestion of NSAIDs, over-the-counter drugs such as aspirin and ibuprofen, was collected in 341 consecutive newly diagnosed breast cancer patients at the Moffitt Cancer Center. This information was correlated with measurements of tumor size, involvement of lymph nodes, estrogen/progesterone receptor status, and studies of cell DNA content (ploidy) and what fraction of cells were dividing and making new DNA. Increased ingestion of NSAIDs over the 5 years correlated with the degree of involvement of lymph nodes (p=0.01), and with smaller tumor size (less than 2.0 cm) correlated with increasing NSAIDs ingestion(p=0.02). Hormone receptor status and the DNA functions did not significantly correlate with NSAIDs ingestion.
September, 1995
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