[ CancerWeb Home
| Comments
| Up One Level ]
Original Summaries of Selected CANCERLIT Records
I-125 Implantation Coupled with External-beam Radiation as Treatment for Prostate Cancer
Last modified on:
Tuesday, April 20, 1999 10:52:30
Copyright © 1994-2008, Information Ventures, Inc.
Radiation therapy is a therapeutic modality available for treating
prostate cancer, but its use can create serious urinary tract
problems. Efforts to localize the radiation are important elements
in making this approach more effective. The November update cites
a study by a group at DeKalb Medical Center in Atlanta, Georgia
(Critz; ICDB/95613788). I-125 implantation has not proven very
effective for prostate cancer, but when coupled with external-beam
radiation and monitoring with serum PSA, the results are
encouraging. The projected disease-free survival rate for the
group of patients is estimated as 74% at 5 years and 66% at 10
years. In 175 patients, the average PSA was 12.6 ng/ml(median 7.7,
range 0.3-188). A PSA level of less than or equal to 0.5 ng/ml was
achieved by treatment in 76% of 101 patients at risk for a minimum
of 60 months; in these patients the disease-free survival rate is
88%. Sexual potency is maintained 5 years post-treatment in 76% of
sexually active patients. These findings are entirely comparable
to surgery and might be improved by ultrasound-guided transperineal
implantation.
November, 1995
Copyright (c) 1994-2008, Information Ventures, Inc.
Mail us at: Customer-Service@infoventures.com
http://infoventures.com