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Original Summaries of Selected CANCERLIT Records
Differences Between African Americans and Caucasians in Incidence and Survival
Last modified on:
Tuesday, April 20, 1999 10:52:32
Copyright © 1994-2008, Information Ventures, Inc.
Race - Differences between African Americans and Caucasians in incidence and survival for certain cancers continue to defy easy explanations, such as socioeconomic status. One recent study (ICDB/95609423) was based on data from the 1217 patients with primary CNS tumors diagnosed before age 15 years between 01/01/70 and 12/31/89 from the population-based Greater Delaware Valley Pediatric Tumor Registry. Of the cases, 656 (54%) were male, 1019 (84%) were white, 1061 (87%) had histologic confirmation and 1045 (86%) were classified as malignant. There were 762 (63%) glial tumors, 238 (20%) medulloblastoma/primitive neuroectodermal tumors (MB/PNET), and 217 (18%) other diagnoses. Medical insurance status, as a proxy for socioeconomic status (SES), was available for more than 85% of the cases; 21% were defined as 'lower SES'. Kaplan-Meier survival analysis indicated that white children have better survival than do black children overall (p less than 0.001) and for glial tumors (p less than 0.001); differences between races for other CNS tumors were not significantly different. Cox proportional hazards analysis confirmed that only race (and not SES, stage of disease at diagnosis, or the duration of symptoms prior to diagnosis) was related to survival overall and for glial tumors separately.
September, 1995
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