Electromagnetic Field Toxicology Reporter

Evaluation and Assessment of Extremely Low Frequency EMF Bioeffects
Volume 1, Number 4, December 1999

Cellular Effects

by Robert B. Goldberg, Ph.D., Editor

Copyright © 1994-2008, Information Ventures, Inc.


Summary

A report is reviewed which details an extensive series of experiments performed over several years looking at EMF effects on ornithine decarboxylase (ODC) activity. Because ODC is an enzyme associated with growth and cell proliferation, any effects of EMF on ODC would have implications for carcinogenic effects also. Three papers are summarized and discussed which report on stimulation of differentiation and growth of primoridal cells and nerve cells by exposure to EMF. Because chemicals that act as tumor promoters are known to reduce gap junction connectivity in cell cultures, a paper is reviewed which attempts to determine if EMF exposure enhanced the effect of tumor promoters. An interesting study demonstrating EMF effects is one in which the author examined the effects of a sinusoidal 7-G, 60-Hz oscillating magnetic field on mutations induced in the hypoxanthine-guanine phosphoribosyl transferase (HPRT) gene gamma radiation. Similarly, another group examined the effects of high density ELF magnetic fields on the induction of sister chromatid exchanges in mouse cells in the presence or absence of mitomycin-C. [four pages, 9 references].

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