Electromagnetic Field Toxicology Reporter

Evaluation and Assessment of Extremely Low Frequency EMF Bioeffects
Volume 2, Number 1, March 2000

Cellular Effects

by Robert B. Goldberg, Ph.D., Editor

Summary

In investigations of the effects of ELF EMFs on cellular proliferation, a group of Italian investigators looked at thymidine uptake into the DNA of human normal osteoblasts and osteosarcoma cell lines, and a group from the UK examined normal human fibroblasts derived from fetal female lung tissue. Research groups in the United States examined cellular differentiation in a rat model of decalcified bone matrix-induced ossification in rats exposed to 60-Hz fields, and in human cells. Many researchers have been studying the effects of EMF on ornithine decarboxylase activity because of its role in cell proliferation and differentiation and one study on this issue is discussed. An Italian research group studied the effects of 50-Hz pulsed EMF on production of cytokines, tumor necrosis factor and interferon-gamma by resting human peripheral blood leukocytes. A report from the M.D. Anderson Cancer Center that summarized confounding factors in studies of EMF bioeffects was discussed. Two studies on the medical possibilities for wound healing by EMFs are presented, and two additional articles examine the physiological basis for a wound healing effect. [seven pages, 18 references].

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