Electromagnetic Field Toxicology Reporter

Evaluation and Assessment of Extremely Low Frequency EMF Bioeffects
Volume 2, Number 2, June 2000

Cellular Effects

by Robert B. Goldberg, Ph.D., Editor

Summary

The effects of EMF on cellular proliferation have been extensively studied. In this issue we discuss reports from a Japanese group studying the effects of a magnetic field on cell proliferation by measuring changes in mitochondrial production of succinate-dehydrogenase, and another by an Italian group measuring effects of exposure to an electric field by monitoring labeled thymidine uptake. Mutation rates after exposure to extremely low frequency (ELF) magnetic fields were investigated by one group studying mutation in the hypoxanthine guanine phosphoribosyl transferase gene in Chinese hamster cells, and by another group studying induction of micronuclei in cultures of amniotic fluid cells. Researchers in the UK examined the effects of ELF EMF on cell immortalization using Syrian hamster dermal cells. Effects of EMFs on gene expression were examined in a number of studies. Two used ELF magnetic fields and the other two looked at the effects of pulsed magnetic fields. Finally we compare results of experiments on the effects of magnetic fields on transcription in cell-free systems prepared from bacteria with those based on human cell components. [ten pages, 20 references].

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