EMF Database abstract: MEASUREMENTS OF DNA DAMAGE FOLLOWING EXPOSURE TO RADIOFREQUENCY RADIATION (MEETING ABSTRACT).

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Last modified on: Monday, July 31, 2000
Copyright © 1994-2008, Information Ventures, Inc.

MEASUREMENTS OF DNA DAMAGE FOLLOWING EXPOSURE TO RADIOFREQUENCY RADIATION (MEETING ABSTRACT).
(Eng.) Roti Roti, J. L.; Malyapa, R. S.; LaGroye, I.; Anane, R.; Li, L.; Zhang, P.; Moros, E.; Straube, W.; Pickard, W. [Washington Univ., St. Louis, MO 63108] Bioelectromagnetics Society, 22nd Annual Meeting, 11-16 June, Munich, Germany, Abstract No. 18-2, p. 101; 2000
Funding: Motorola Corp.

Since DNA damage is believed to be a first step in mutagenesis and for many mechanisms of neoplastic transformation, the determination of whether or not a given agent induces DNA damage in exposed cells is an important factor in the assessment of its mutagenic or carcinogenic potential. Because of the concern regarding the carcinogenic potential of some forms of radiofrequency radiation and of reports that 2450 MHz microwaves caused DNA damage (Lai and Singh, Bioelectromagnetics 16:207-210, 1995), we measured DNA measurement damage following exposure to 2450 MHz (CW and pulsed) microwaves (SAR 0.6-1.9 W/kg), 835.62 MHz frequency modulated continuous wave (FDMA) and 847.74 MHz code division multiple access (CDMA)(SAR 0.6-5 W/kg) radiations. Recent work includes studies with iDEN and TDMA (2.4-26 mW/kg). Because of its sensitivity and the ability to measure DNA damage on a cell by cell basis, we used the alkaline comet assay. Over the past 5 yr three different teams have conducted different sets of these experiments. Using the alkaline comet assay as described by Olive et al. (Exp Cell Res 198:259-267), all the teams were able to detect DNA damage following irradiation of cultured cells with 0.6-1.0 cGy of 137Cs gamma-rays, but not in any of the RF studies completed so far. Thus, we conclude that RF radiation is not robust inducer of DNA damage. (1 Ref). [Copyright 2000, Information Ventures, Inc.]

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