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Medical Subject Headings — A Background

The National Library of Medicine (NLM) is the largest medical library in the world. Its beginnings date to before the American Civil War. Since 1879, NLM has prepared an index for articles published in biomedical journals. From that first manuscript catalog, the service continues into the 21st century in the form of MEDLINE® and other computer-produced information databases. Over time, in order to arrange the contents in a useful way, a controlled vocabulary has been developed for the NLM index. Beginning in 1960, the Library restructured the vocabulary to function in a machine-retrieval environment. There are now over 40 years of knowledge available online for analysis by researchers.

MeSH®, the National Library of Medicine's controlled vocabulary thesaurus, is recognized as the authority for cataloging and indexing scientific terms. It consists of sets of terms with descriptors in a hierarchical structure that permits searching at various levels of specificity. At the most general level of the hierarchical structure are very broad headings such as "Anatomy" or "Diseases." At more narrow levels are specific headings such as "Sternum" and "Scabies." There are approximately 22,000 descriptors in MeSH®. In addition to these headings, there are over 132,000 headings called Supplementary Concept Records within a separate chemical thesaurus. There are also thousands of cross-references that assist in finding the most appropriate MeSH® Heading.

MeSH® is used by NLM for indexing articles from approximately 4,600 of the world's leading biomedical journals for the MEDLINE database. It is also used for other NLM-produced databases that include cataloging of books, documents, and audiovisuals acquired by the Library. Pharmaceutical companies use MeSH® for indexing their corporate information. Each bibliographic reference is associated with a set of MeSH® terms that describe the content of the item. Similarly, search queries use MeSH® vocabulary to find items on a desired topic. MeSH® is the source of the descriptors used in NLM's Index Medicus® and is fundamental to the organization of this monthly guide to articles from more than 3,700 international journals.

The MeSH® vocabulary is continually revised and updated by staff experts. New terms are added as they appear in the scientific literature or in emerging areas of research and are defined within the context of existing vocabulary.

Indexers must hold an advanced degree in one of the biomedical sciences and complete an extensive and rigorous training regimen at NLM facilities in Bethesda, Maryland. Journal assignments are based on each indexer’s subject and language capabilities and experience. Stringent deadlines apply, since rapid processing is required to ensure that citations in MEDLINE® are current.


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