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AGRICULTURAL-INDUSTRY
PESTICIDES-EXPOSURE
CHROMOSOME-DAMAGE

FREQUENCY OF SISTER CHROMATID EXCHANGE AND HEMATOLOGICAL EFFECTS IN PESTICIDE-EXPOSED GREENHOUSE SPRAYERS

The effect of pesticides in greenhouse workers was evaluated by hematological parameters and frequency of sister chromatid exchanges (SCE). The subjects were 134 healthy greenhouse workers employed in 52 nurseries. There were almost 50 different pesticides used by sprayers during the 5 months prior to the blood sampling, including insecticides, fungicides, and growth regulators. After adjusting for smoking and age, a significantly higher mean SCE frequency was observed for nonsmoking greenhouse workers compared to nonsmoking, unexposed referents. The mean frequency of SCE showed a slight dose-related increase with decreasing use of protective equipment. The authors conclude that combined subtoxic occupational pesticide exposure may have a genotoxic effect.

Scandinavian Journal of Work, Environment and Health, 21(4):283-288, 1995. (32 references)

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