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A case of photoallergic dermatitis caused by mancozeb was summarized. A 56 year old male with severe eczema that occurred primarily on sun exposed areas was evaluated. Patch and photopatch testing using a unspecified allergen series was performed. Reactions read 2 and 3 days later revealed that the patient reacted only to Zimandithane an agricultural fungicide. Further patch and photopatch testing was performed with the components of Zimandithane, mancozeb and the vehicle lignin-sulfonic-acid, calcium-salt. Mancozeb produced positive responses after 2 and 3 days. The patient avoided further contact with mancozeb; however, he demonstrated photosensitivity 5 months later after a 20 minute exposure to sunlight. This indicated that the patient had developed mancozeb induced photoallergic contact dermatitis. The authors conclude that although mancozeb has been shown to cause contact dermatitis, this is the first documented case of mancozeb inducing photoallergic contact dermatitis. The physicochemical properties of mancozeb relevant to its phototoxicity were summarized.
Contact Dermatitis, 35(3):183, 1996. (2 references)
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