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A study of the prevalence of sister chromatid exchanges (SCEs) in lymphocytes (blood cells) of phosphate fertilizer workers was conducted. The study included of 40 workers employed at a Chinese fertilizer factory and 40 university staff members who served as comparisons. The mean SCE frequency in the exposed workers was significantly higher than in the comparisons. The SCE frequencies in the exposed workers increased with increasing length of employment at the factory up to 10 years, but were decreased for longer periods. The authors conclude that air pollutants at the phosphate fertilizer factory, primarily fluorides, can induce SCEs in human lymphocytes.
Mutation Research, 334(2):243-246, 1995. (13 references)
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