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OIL-AND-GAS-INDUSTRY
GASOLINE
DNA-DAMAGE

DNA SINGLE STRAND BREAK ANALYSIS IN MONONUCLEAR BLOOD CELLS OF PETROL PUMP ATTENDANTS

DNA single strand breaks and DNA adducts were measured in blood cells collected from 35 male gas station attendants and 32 control subjects. The subjects were questioned with regard to lifestyle, work histories, prior exposures to carcinogens and ionizing radiation, and medical histories. A statistically insignificant increase in DNA single strand breaks was observed in the exposed group. Attendants were regrouped based upon exposure characteristics; attendants who worked at the gasoline pumps more than 4 hours a day, and those who worked at the pumps less than 4 hours a day. Attendants who worked more than 4 hours at the pumps exhibited a significant increase in DNA single strand breaks between samples from Monday and Friday. Nonsmoking attendants working at the pumps less than 4 hours exhibited no significant increase.

International Archives of Occupational and Environmental Health, 67(1):35-39, 1995. (27 references)


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