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ORGANIC-SOLVENTS
BIOLOGICAL-MONITORING
URINE-CHEMISTRY

BIOLOGICAL MONITORING OF WORKERS EXPOSED TO N-N-DIMETHYLFORMAMIDE. II. DIMETHYLFORMAMIDE AND ITS METABOLITES IN URINE OF EXPOSED WORKERS

The relationship between occupational exposure to N,N-dimethylformamide (DMF) and the urinary concentrations of this solvent and its metabolites were investigated by analyzing the urine of 22 exposed workers in a synthetic leather factory. Nineteen unexposed workers served as a control group. Air concentrations of DMF ranged from 10mg/m3 to 20mg/m3. The urinary levels of DMF and its metabolites were determined by gas chromatography/mass spectrometry. The results demonstrated the value of urinary concentrations of DMF and N-methylformamide for use as biological markers for exposure to DMF.

International Archives of Occupational and Environmental Health, 67(1):47-52, 1995. (27 references)

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