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Data from 12 case control studies conducted in seven countries were pooled and reanalyzed in an effort to examine the relationship between wood dust and sino/nasal cancer. There was a high risk of adenocarcinoma among male employees in wood related occupations, with the greatest risk found for those in jobs with the highest wood dust exposure and increased duration of exposure. The risk of adenocarcinoma was also greater among women employed in wood related jobs. An excess of squamous cell carcinoma appeared in women in dust exposed jobs, which increased with the duration of exposure, but only men employed for 30 or more years showed an increased risk of squamous cell carcinoma. The authors conclude that the study provides strong support to the link between wood dust exposure with various occupations and the risk of sino/nasal adenocarcinoma, but the evidence with regard to squamous cell carcinomas is ambiguous.
American Journal of Industrial Medicine, 28(2):151-166, 1995. (36 references)
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